Polynucleotides Treatment
Polynucleotides are renowned for their regenerative properties, promoting tissue repair, fibroblast stimulation and collagen synthesis – a great anti-ageing treatment. Polynucleotides can address various skin concerns, including fine lines, wrinkles, scars, rosacea, inflammation and overall skin quality. They offer a versatile solution suitable for various skin types and concerns, you can treat the face, eye contour area, upper arms and necks.
In clinic we use a NEW game changing formulation of Polynucleotides, Niacinamide, and Hyaluronic acid with 3 molecular weights by Sky Medic. The perfect synergy for optimal dermal bioregenerative rejuvenation. This treatment involves a light peel followed by micro needling of the Polynucleotides, Niacinamide & Hyaluronic Acid into the skin.

Benefits of Polynucleotides
- Boosting collagen production and elastin
- Enhancing skin hydration, circulation and overall skin quality.
- Reduce dark under-eye circle, smooth out Crow’s feet, fine lines, hollows and puffiness beneath the eyes.
- Smooth, fine lines encourage glowing skin
- Improve the folds and lines, tightening and lifting cheeks around nasolabial lines
- Improve the lines around the mouth without plumping or adding volume.
- Help to tighten and define the jawline.
- Help improve fine lines and crepey-looking skin.
Microneedling Benefits with PRDN
The benefit of the using microneedling to work the Polynucleotides & Hyaluronic Acid solution into the skin, as it will enhance results due to the active collagen formation from the micro needling. Treatment includes mini peel and super hydrating mask.
What are Polynucleotides.?
Polynucleotides (PDRN) is a regenerative ingredient from salmon DNA that enhances skin repair, reduces wrinkles, and boosts elasticity. Polynucleotide (PDRN) promotes angiogenesis, cellular activity, collagen synthesis, soft tissue regeneration, and skin priming and revitalisation.
More medical detailed information about Polynucleotides can be found at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10308489/
Polynucleotides Treatment – How long in between treatments?
It is recommended interval between each treatment is at least 3 weeks. A course of 3 treatments is advised for optimal results.
How many treatments do I have to do before seeing results?
It may take up to four weeks to begin seeing results, but it will be two months after the second treatment before the most noticeable results are visible. Individual results may vary, and cannot guarantee specific outcomes as they are influenced by various factors unique to each person.
Eyes – £180 / Course of 3 – £490
Face – £250 / Course of 3 – £730
Neck – £200 / Course of 3 – £550
Face & Neck – £340 / Course of 3 – £1000
Décolleté – £300 / course of 3 – £885
Face, Neck & Décolleté – £390 / course of 3 – £1155
Upper arms – £400 / Course 3 – £1170

Advanced Radio Frequency & Polynucleotides Microneedling Combined
Combing the power of Radio Frequency to help produce collagen further and tighten skin followed by Polynucleotides Microneedling. Radiofrequency (RF) stimulates the production of collagen, resulting in the immediate tightening of the skin and Microneedling forces the collagen production combined with skin regenerative properties of Polynucleotides this treatment is the next level in anti-ageing without losing any face volume or structure – it will plump the skin!
Radio Frequency delivers heat deep straight into the dermis and subcutaneous tissue to activate elastin fibres and collagen to regenerate damaged tissue. It also enhances lymphatic drainage and assists speeding up toxin removal from the skin, resulting in smoother, firmer skin.
Treatment includes mini peel and super hydrating mask.
Prices Advanced Radio Frequency & Polynucleotides
Face – £300 / Course 3 £800
Neck – £250 / Course 3 £730
Face & Neck – £400 / Course 3 £1180
Upper arms – £450 / Course 3 £1330
NEW TREATMENT…!!!
NEW EXOFUSION Exosome & PDRN Microneedling
Adding more powerful ingredients than ever into microneedling with the EXO FUSION, an advanced regenerative upgrade to traditional microneedling. The treatment combines microneedling with plant and probiotic-derived exosomes and PDRN (polynucleotides) to support the skin’s natural repair and renewal processes. Exosomes act as messenger particles that help speed up skin cell communicate and regeneration, while PDRN encourages healing, collagen production and improved skin strength. Together they deliver powerful active ingredients deep into the skin to improve overall skin quality rather than just the surface.


Pricing EXOFusion & PDRN Microneedling
Eyes – £200 / Course 3 £550
Face – £270 per treatment | Course of 3 £750
Neck – £220 / Course 3 £550
Face & Neck – £360 per treatment | Course of 3 £1000
Décolleté – £320 per treatment | Course of 3 £945
Face, Neck & Décolleté – £410 /course of 3 – £1170
Upper arms – £450 / Course 3 – £1330
All treatments include a super hydrating bio-cellulose mask.
NEW Advanced Radio Frequency with PDRN & EXOFusion Exosomes Microneedling
Taking the results up further by combing the power of Radio Frequency to help produce collagen further and tighten skin followed by Polynucleotides & Fusion Exosomnes Microneedling – this is total skin rejuvenation at its best. Radiofrequency (RF) stimulates the production of collagen, resulting in the immediate tightening of the skin and Microneedling forces the collagen production combined with skin regenerative properties of Polynucleotides this treatment is the next level in anti-ageing without losing any face volume or structure – it will plump the skin!
Radio Frequency delivers heat deep straight into the dermis and subcutaneous tissue to activate elastin fibres and collagen to regenerate damaged tissue. It also enhances lymphatic drainage and assists speeding up toxin removal from the skin, resulting in smoother, firmer skin. Treatment includes mini peel and super hydrating mask.
Prices Radio Frequency with Polynucleotide & EXO Fusion Exosomes
Face – £320 / Course 3 £900
Neck – £260 / Course 3 £710
Face & Neck – £420 / Course 3 £1200
Upper arms – £480 / Course 3 £1380
Polynucleotides Treatment – Frequently Asked Questions
What is the difference between Polynucleotides & Skin Boosters..?
Polynucleotides go a step further by activating fibroblast cells within the skin, unlocking your skin’s natural regenerative potential. While skin boosters provide immediate results such as plumping and hydration.
Can Polynucleotides be combined with other aesthetic procedures?
Yes, Polynucleotides complement nearly all aesthetic treatments, offering a synergistic approach for comprehensive results. Combining treatments enhances overall facial rejuvenation.
What skin concerns can Polynucleotide treatments address?
A wide range of skin concerns: fine lines, wrinkles, scars, rosacea, inflammation and overall skin quality.
How are Polynucleotides different to other treatments like fillers or anti-wrinkle injections?
Filler and/or anti-wrinkle injections address wrinkles or volume loss. Polynucleotide treatments focus on skin regeneration and quality. Polynucleotides stimulate natural fibroblasts and collagen production, enhancing skin texture, hydration and elasticity over time.
Pre-treatment Advice
- Avoid alcohol for 24 hours prior to treatment, as this increases the risk of bruising.
Polynucleotides Treatment – Aftercare Advice
After treatment, most people can resume their normal daily activities.
- Avoid touching the treatment areas for 12 hours after the treatment. After that, the area can be washed with a gentle cleanser
- Avoid active topical skincare i.e. AHA, BHA, Alcohol, Retinol
- Avoid cosmetic make-up for up to 24-48 hours post-treatment, unless you have mineral make-up i.e. Jane Iredale Mineral make-up or equivalent
- Avoid strenuous exercise and swimming for 48 hours to avoid the risk of infection.
- Do not use steam, sauna, sunbeds or sunbathe for at least 7 days
- Try to avoid touching or rubbing the treated areas
- Drink as much water as possible
- Avoid spray tanning or self-tan for 14 days