
Polynucleotides and Exosomes Treatments – At RR Skin, Body & Laser Clinic in Dartford, Kent, we are proud to be at the forefront of cutting-edge aesthetic treatments. This month, we are excited to introduce Exosome therapy to our advanced skin treatment menu, joining our popular Polynucleotide (PDRN) microneedling treatments. These two regenerative therapies are revolutionising the world of skin rejuvenation, each with unique properties and outstanding results.
But what exactly are Polynucleotides and Exosomes? And how do they differ? Let’s explore these powerful Polynucleotides and Exosomes treatments and why they’re the future of non-surgical skin regeneration.
What Are Polynucleotides?
Polynucleotides (PDRN) are chains of nucleotides – building blocks of DNA – that are derived from purified, natural sources. These molecules stimulate the body’s natural ability to repair and regenerate skin tissue. Polynucleotide therapy works on a cellular level to deeply hydrate, reduce inflammation, improve skin elasticity, and accelerate tissue healing.
In the clinic, we use SkyMedic’s premium-grade PDRN products, a globally trusted Spanish aesthetics manufacturer known for its innovative research and clinical-grade skincare solutions. Their polynucleotide formulations offer superior bioavailability and efficacy, making them a top choice for aesthetic professionals worldwide.
What Are Exosomes?
Exosomes are nano-sized extracellular vesicles naturally secreted by stem cells. They act as messengers, delivering growth factors, peptides, proteins, and genetic material to skin cells. Exosome therapy is at the cutting edge of regenerative aesthetics, helping to stimulate collagen production, improve skin texture, reduce pigmentation, and support anti-ageing at a cellular level.
We are thrilled to launch Exosome treatments using Innoaesthetics’ latest INNO EXOMA EXO-SKIN product. Innoaesthetics is an industry leader with decades of experience in medical-aesthetic formulations. Their exosome technology is clinically developed to ensure optimal purity and stability, backed by extensive dermatological research and real-world results.
Polynucleotides and Exosomes Treatments – Key Differences Between Polynucleotides and Exosomes
While both treatments promote skin regeneration, they work in distinctly different ways:
| Feature | Polynucleotides (PDRN) | Exosomes |
| Source | DNA fragments (typically salmon derived) | Stem cell-derived nano-vesicles |
| Mechanism | Stimulates tissue repair, reduces inflammation | Delivers cell-signalling molecules for rejuvenation |
| Ideal for | Deep hydration, skin healing, rosacea, fine lines | Anti-ageing, pigmentation, elasticity, overall rejuvenation |
| Action | Rebuilds skin from DNA level | Reprograms skin cells to regenerate faster |
Polynucleotides and Exosomes Treatments – Microneedling Delivery – Enhancing Results
In clinic, both treatments are expertly applied using a microneedling device technique. Microneedling creates micro-channels in the skin, allowing for deeper and more effective penetration of the active ingredients. It also stimulates the skin’s natural collagen production for enhanced rejuvenation.
Combining microneedling with Polynucleotides or Exosomes supercharges the skin’s healing response, leading to firmer, clearer, and younger-looking skin with minimal downtime.
Benefits of Polynucleotide (PDRN) Treatment
Polynucleotide therapy, delivered through microneedling, is especially effective for patients experiencing skin sensitivity, dehydration, and visible signs of ageing. Here’s how it helps:
- Sensitive or Inflamed Skin
Polynucleotides have powerful anti-inflammatory properties that calm irritated skin and support barrier repair – making them ideal for those with rosacea, redness, or sensitivity. - Dehydrated and Dull Complexion
By improving cellular hydration from within, PDRN helps dry/dehydrated skin retain moisture more effectively, resulting in a fresher, plumper, and more luminous appearance. - Acne Scarring and Skin Damage
This treatment accelerates tissue regeneration and healing, helping to smooth acne scars, reduce post-inflammatory pigmentation, and repair sun damage. - Fine Lines and Skin Laxity
Polynucleotides stimulate fibroblast activity, which increases collagen and elastin production – leading to firmer, more elastic skin and a visible reduction in fine lines. - Post-Treatment Recovery Support
Ideal for use after laser treatments, microneedling, or chemical peels, PDRN promotes faster recovery by enhancing skin regeneration and reducing downtime.
Learn more about our polynucleotides treatment
Benefits of Exosomes Treatment
Exosome therapy offers a highly advanced approach to skin rejuvenation, targeting the signs of ageing, pigmentation, and overall skin quality with precision.
- Uneven Skin Tone and Hyperpigmentation
Exosomes regulate melanin production and accelerate skin turnover, helping to fade dark spots, age spots, and uneven pigmentation for a clearer complexion. - Ageing and Wrinkled Skin
Rich in growth factors and peptides, exosomes signal skin cells to regenerate and produce collagen – visibly reducing wrinkles and improving firmness. - Rough Texture and Enlarged Pores
This treatment refines skin texture and minimises the appearance of pores by promoting healthy cell renewal and smoothing the skin surface. - Stressed, Tired-Looking Skin
Exosomes revitalise the skin at a cellular level, restoring a youthful glow and improving tone, elasticity, and resilience over time. - Slow Healing or Post-Treatment Skin
When used after microneedling or other procedures, exosomes significantly reduce inflammation and boost recovery by accelerating the skin’s natural healing processes.
Learn more about our exosomes treatment
Why Choose RR Skin, Body & Laser Clinic to come and have Polynucleotides and Exosomes Treatments?
As Dartford’s premier destination for advanced skin aesthetics, we are dedicated to bringing the latest scientific innovations to our clients. Our highly trained and award-winning skin specialist, industry-leading products, and personalised treatment plans ensure exceptional results for every skin type.
Whether you’re looking to rejuvenate tired skin, improve tone and texture, or combat the signs of ageing, our Polynucleotide and Exosome treatments offer a truly transformative experience.
If you want to discuss this treatment and your skin concerns, then book a consultation via our online booking system.